The primary site of action of FSH is the Sertoli cell (Fig. 11.6). The biochemical events that follow the binding of FSH to its receptor on the cell surface are similar to those for LH. The elevation of Sertoli cell cAMP activates cAMP-dependent protein kinase and stimulates synthesis of mRNAs and proteins, including androgen-binding protein (ABP) (Fig. 11.6) and aromatase.
